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Generic Name: copanlisib (KOE pan LIS ib)
Brand Names: Aliqopa
Aliqopa (copanlisib) is used to treat follicular lymphoma. Includes Aliqopa side effects, interactions and indications.
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Drug Information:
Aliqopa (copanlisib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Aliqopa is used to treat follicular lymphoma that has relapsed after treatment with at least two other medicines. Aliqopa was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, people with follicular lymphoma responded to this medicine. However, further studies are needed. Serious and sometimes fatal infections may occur during treatment with Aliqopa. Call your doctor right away if you have signs of infection such as: fever, chills, mouth sores, a new or worsening cough, or trouble breathing. Learn more

Aliqopa Side Effects

Aliqopa Side Effects

Note: This document contains side effect information about copanlisib. Some of the dosage forms listed on this page may not apply to the brand name Aliqopa.

For the Consumer

Applies to copanlisib: intravenous powder for solution

Along with its needed effects, copanlisib (the active ingredient contained in Aliqopa) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking copanlisib:

More common

  • Black, tarry stools
  • bleeding gums
  • blood in the urine or stools
  • blurred vision
  • chest pain
  • chills
  • cough
  • cracks in the skin
  • dizziness
  • dry mouth
  • fatigue
  • flushed, dry skin
  • fruit-like breath odor
  • headache
  • increased hunger
  • increased thirst
  • increased urination
  • loss of heat from the body
  • lower back or side pain
  • nausea
  • nervousness
  • painful or difficult urination
  • pale skin
  • pinpoint red spots on the skin
  • pounding in the ears
  • red, swollen skin
  • scaly skin
  • slow or fast heartbeat
  • sneezing
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • stomach pain
  • sweating
  • swollen glands
  • tightness in the chest
  • troubled breathing
  • unexplained weight loss
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting

Some side effects of copanlisib may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • cracked lips
  • diarrhea
  • difficulty in swallowing
  • lack or loss of strength
  • swelling or inflammation of the mouth

For Healthcare Professionals

Applies to copanlisib: intravenous powder for injection


The most common (20% or greater) adverse reactions were hyperglycemia, decreased hemoglobin, decreased lymphocyte count, decreased white blood cell count, decreased platelet count, decreased neutrophil count, hypertriglyceridemia, hypophosphatemia, diarrhea, decreased general strength and energy, hypertension, leukopenia, neutropenia, nausea, hyperuricemia, thrombocytopenia, lower respiratory tract infections, and increased serum lipase.


Very common (10% or more): Hyperglycemia (95%)


Very common (10% or more): Decreased hemoglobin (78%), decreased lymphocyte count (78%), decreased white blood cell count (71%), decreased platelet count (65%), decreased neutrophil count (63%), leukopenia (36%), neutropenia/febrile neutropenia (32%), thrombocytopenia (22%)


Very common (10% or more): Hypertriglyceridemia (58%), hypophosphatemia (44%), increased serum lipase (21%)


Very common (10% or more): Diarrhea (36%), nausea (26%), stomatitis/oral pain/oropharyngeal erosion and ulcer (14%), vomiting (13%)


Very common (10% or more): Decreased general strength and energy/fatigue/asthenia (36%)

Common (1% to 10%): Mucosal inflammation


Very common (10% or more): Hyperuricemia (25%)


Very common (10% or more): Lower respiratory tract infections (21%)

Common (1% to 10%): Pneumonitis

Nervous system

Common (1% to 10%): Paresthesia, dysesthesia


Very common (10% or more): Rash/exfoliative skin reactions (15%)


Very common (10% or more): Hypertension/secondary hypertension (13%)

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Aliqopa