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Generic Name: fremanezumab-vfrm (FREE ma NEZ ue mab)
Brand Names: Ajovy
Ajovy (fremanezumab-vfrm) is a preventive migraine treatment. Includes Ajovy side effects, interactions and indications.
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Drug Information:
Ajovy (fremanezumab-vfrm) is an injectable prescription medicine used to prevent migraine headaches in adults. Ajovy works by blocking the activity of calcitonin gene-related peptide (CGRP). Ajovy may also be used for purposes not listed in this medication guide. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. You should not use Ajovy if you are allergic to fremanezumab-vfrm. Learn more

Ajovy Side Effects

Ajovy Side Effects

Note: This document contains side effect information about fremanezumab. Some of the dosage forms listed on this page may not apply to the brand name Ajovy.

For the Consumer

Applies to fremanezumab: subcutaneous solution

Along with its needed effects, fremanezumab (the active ingredient contained in Ajovy) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking fremanezumab:

More common

  • Fast heartbeat
  • fever
  • hives, itching, skin rash
  • hoarseness
  • irritation
  • joint pain, stiffness, or swelling
  • redness of the skin
  • swelling of the eyelids, face, lips, hands, or feet
  • tightness in the chest
  • troubled breathing or swallowing

Some side effects of fremanezumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

For Healthcare Professionals

Applies to fremanezumab: subcutaneous solution


The most commonly reported adverse reaction during clinical trials was injection site reactions.


Very common (10% or more): Injection site reactions (up to 45%)

Injection site reactions included injection site pain, induration, erythema, and pruritus.


Uncommon (0.1% to 1%): Hypersensitivity reactions


Common (1% to 10%): Anti-Drug-Antibodies

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Ajovy