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Generic Name: benzoyl peroxide and clindamycin topical (BEN zoyl per OX ide and clin da MYE sin)
Brand Names: Acanya, BenzaClin, BenzaClin with pump, Duac, Z-Clinz 10, Z-Clinz 5
Acanya Gel(benzoyl peroxide and clindamycin phosphate) is used to treat acne. Includes Acanya side effects, interactions and indications.
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Drug Information:
Acanya Gel contains a combination of benzoyl peroxide and clindamycin. Benzoyl peroxide has an antibacterial effect. It also has a mild drying effect that allows excess oil and dirt to be washed away. Clindamycin is an antibiotic that prevents bacteria from growing on the skin. Acanya Gel is used to treat acne vulgaris in patients 12 years or older. Acanya may also be used for purposes not listed in this medication guide. Use Acanya exactly as your doctor has prescribed it for you. Using more medicine or applying it more often than prescribed will not make it work any faster, and may increase side effects. Do not use this medication for longer than your doctor has prescribed. Learn more

Acanya Side Effects

Acanya Side Effects

Note: This document contains side effect information about benzoyl peroxide / clindamycin topical. Some of the dosage forms listed on this page may not apply to the brand name Acanya.

In Summary

Common side effects of Acanya include: xeroderma. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to benzoyl peroxide/clindamycin topical: external gel, external kit

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad irritation where this drug is used.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Irritation where this drug is used.
  • Dry skin.
  • Itching.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to benzoyl peroxide/clindamycin topical: topical gel, topical kit


The most frequently reported side effects were erythema, scaling, peeling, dry skin, and itching.


Very common (10% or more): Erythema (up to 28%), scaling (up to 19%), peeling (up to 17%), dry skin (up to 15%), itching (up to 15%)

Common (1% to 10%): Pruritus, sunburn, burning, stinging

Uncommon (0.1% to 1%): Contact dermatitis, rash, acne worsened

Postmarketing reports: Urticaria


Frequency not reported: Colitis

Postmarketing reports: Pseudomembranous colitis, hemorrhagic diarrhea, diarrhea, abdominal pain


Postmarketing reports: Anaphylaxis, allergic reaction


Common (1% to 10%): Application site reaction

Uncommon (0.1% to 1%): Application site pain, application site exfoliation, application site irritation

Postmarketing reports: Discoloration

Nervous system

Common (1% to 10%): Headache

Uncommon (0.1% to 1%): Paresthesia

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Acanya